Located in Rockingham County, Mayo River State Park offers various recreational opportunities at the main Mayo Mountain access and at multiple accesses along the Mayo River.
At the main access, visitors can enjoy hiking trails, fishing ponds, a picnic area and shelter, and a group campsite. Four accesses — Deshazo Mill, Anglin Mill, Hickory Creek, and Mayodan — allow entry to the river, home to rich wildlife and Class II rapids. Deshazo Mill also features a picturesque waterfall on Fall Creek.